gut complaints
Conditions
Interventions
The intervention group receives 5.5 g GOS in powder form. The control group
receives the same amount of maltodextrin powder. Both groups need to use these
powder supplements, portion packed in sache
Sponsors
Campina
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Female - 25 - 45 years of age - Component (summed) score for gut complaints * 6 (based on bloating, flatulence, stomach ache, constipation, diarrhea)
Exclusion criteria
Exclusion criteria: - Any medical diagnosed disease underlying gut-related complaints, including Irritable Bowel Syndrome, celiac disease, Crohn*s disease, colitis, haemorrhoids, cancer, and/or any other disease considered relevant as determined during screening. - Use of antibiotics, opiates, anti-inflammatory drugs (NSAIDs) and/or metformin, and/or other medication that are known to affect the composition of the gut microbiota during the 14 days before inclusion. - Pregnant or lactating. - Self-reported lactose intolerance - Self-reported cow*s milk protein allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary parameter is a component score of gut comfort feelings based on 5 questions regarding bloating, flatulence, stomach ache, constipation and diarrhea of the past 7 days (each answer ranging from 0 -3; thus component score can range from 0-15). | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary objectives are to assess the effects of GOS on the component score of gut comfort at days 4 and 14 and the shifts in microbial composition after 21 days. | — |
Countries
Netherlands
Outcome results
None listed