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Stroke-on-a-chip

Stroke-on-a-chip - Stroke-on-a-chip

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON49951
Enrollment
15
Registered
2020-03-12
Start date
2020-10-07
Completion date
Unknown
Last updated
2026-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebral infarction

Interventions

None listed

Sponsors

Overige Ziekenhuizen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: * Age * 18y * Clinical and radiological diagnosis of acute ischemic stroke * Admission to stroke unit * Capability to provide written informed consent

Exclusion criteria

Exclusion criteria: * Any relevant systemic disease that is expected to interfere with a patient outcome within six months, such as malignancy * Any progressive neurodegenerative disease * Severe aphasia (informed consent not possible)

Design outcomes

Primary

MeasureTime frame
Primary outcome measure is network functionality, where a network is considered functional when a minimum of 1/3 of the electrodes shows activity, with a minimum of 6 spikes per minute per active electrode, and a minimum of one synchronous event per minute at eight weeks after plating.

Secondary

MeasureTime frame
- Electrophysiological responses to simulated *cerebral ischemia* - Network and neuronal properties as studied by immunocytochemical analyses.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP) · Data processed: Jul 23, 2026