Morphology of olfaction-related brain regions and brain functionality in response to odor exposure in healthy participants

Morphology of olfaction-related brain regions and brain functionality in response to odor exposure in healthy participants - Smell it! study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON49925

Enrollment

Registered

2021-12-14

Start date

2022-02-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

reukvermogen anosmia

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Self-reported healthy No known smell disorder No history of head trauma No neurological disorders (like Alzheimer*s or Parkinson*s disease) Labelled as having a normal sense of smell according to our standardized clinical olfactory test Sniffin* Sticks) (score >= 30.5 points out of 48 points) Age between 18-75 years Have normal eyesight or an eye deviation that can be corrected with glasses or contact lenses. Willing to comply with the study procedures Willing to be informed about incidental findings of pathology and approving of reporting this to their general physician Having given written informed consent (see E1.Informatiebrochure)

Exclusion criteria

Exclusion criteria: Having a contra-indication to MRI scanning (including, but not limited to): o Being pregnant o Pacemakers and defibrillators o Intraorbital or intraocular metallic fragments o Ferromagnetic implants o Claustrophobia

Design outcomes

Primary

Measure	Time frame
1) volume of olfaction-related brain areas; 2) activation of brain areas during odor stimulation compared to the control condition.	—

Secondary

Measure	Time frame
1) olfactory function and its relation with the primary study parameters; 2) activation of functional brain networks	—

Countries

Netherlands

Outcome results