Non-invasive lung function measurements in infants using Forced Oscillation Technique and diaphragm electromyography.

Non-invasive lung function measurements in infants using Forced Oscillation Technique and diaphragm electromyography. - Neonatal lung function monitoring

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON49917

Enrollment

Registered

2021-12-14

Start date

2022-02-05

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

respiratory distress syndrome Respiratory insufficiency

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: * Standard monitoring used with ECG electrodes (25/26 weeks postmenstrual age and older) * Intubated due to respiratory failure and and ventilated for >24h with Fabian HFOi neonatal ventilator with an operational FOT modality * Written parental/guardian informed consent

Exclusion criteria

Exclusion criteria: Congenital anomalies that prevent the execution of a dEMG measurement Asphyxiated infants with therapeutical hypothermia Receiving nitric oxide therapy Intubated as part of an end of life decision/ceasing of treatment Intubation as a consequence of non-pulmonary related surgical intervention

Design outcomes

Primary

Measure	Time frame
Reactance values measured with FOT and diaphragm activity measured with dEMG. Both techniques are aimed at examination of lung function over time.	—

Secondary

Measure	Time frame
See primary study parameters	—

Countries

Netherlands

Outcome results