A-specifieke chronische lage rugpijn Back Pain spinal pain
Conditions
Interventions
None listed
Sponsors
Universitair Medisch Centrum Groningen
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: 1. Age >=18 2. Have to experienced back pain more than 3 months 3. Non-specific CLBP confirmed by a physiatrist of UMCG Pain Rehabilitation.Admitted to a 12 week pain rehabilitation program 4. Have reported a minimal pain level of 3 on the 0-10 pain numerical rating scale (NRS) 5. Signed informed consent
Exclusion criteria
Exclusion criteria: 1.. Spinal pathologies, such as fractures, tumours or inflammatory diseases, such as ankylosing spondylitis, nerve root compromise will be confirmed by clinical neurological tests (disk herniation and spondylolisthesis with neurological involvement, infection, malignancy, rheumatic, narrowing of spinal canal and other conditions) or severe cardiorespiratory diseases 2. Diseases affecting sensory processing (eg. diabetes, alcohol or substance abuse, neuropathy) 3. Back surgery in the past 2 years 4. Patients using neuroleptics, benzodiazepines or regular / strong opioids
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The patients with chronic low back pain will be categorized into two subgroups between CS+ and CS-. This will be carried out with the central sensitization inventory (CSI) based on standardized cut-off scores. Main endpoints will be tested in the movement laboratories of both the UMCG-Beatrixoord (patients) and Saxion university of applied sciences (healthy controls). Movement analyses will be performed using Vicon movement analysis system. To test differences in motor control between the groups, we will apply Principal Component Analyses to measure and compare their loadings using motion capture data. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Quantitative Sensory Testing: QST is a psychophysical method that is used to assess the somatosensory function. In this study, the assessment will consist three sensory tests, 1) Cuff-algometry (CA), 2) Temporal Summation of Pain (TSP), and 3) activation of Conditioned Pain Modulation (CPM). These tests will be used in all the three groups. 2. Nummeric Rating Scale for Pain: A pain rating scale will be administered to rate current pain intensity by giving a number between 0 and 10 (0 = no pain, and 10 = maximum pain imaginable). This scale will be used just in the patients groups. 3. Surface Electromyography derived from m. biceps and quadriceps femoris in both lower limbs with 4 EMG sensors. Two EMG sensors are placed at the erector spinae bilaterally. Finally, another 3 EMG sensors at the trapezius descendens, pectoralis major, and anterior deltoid muscules will be placed. all placements will be carried out following SENIAM methods. 4. Ground reaction forces during lifting and gait. | — |
Countries
Netherlands
Outcome results
None listed