normal pro-inflammatory cytokine responses, ECG-responses, and skin conductance-responses to social events N/A
Conditions
Interventions
None listed
Sponsors
Universiteit van Tilburg
Eligibility
Age
12 Years to 17 Years
Inclusion criteria
Inclusion criteria: Adolescents enrolled in the third year of high school
Exclusion criteria
Exclusion criteria: There are no exclusion criteria for participation, but participants with autoimmune diseases and/or a hyperactive thyroid will be excluded from the analyses.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are acute inflammatory responses to the standardized social stressor, including pro-inflammatory cytokines interleukin-8 (IL-18), interleukin-6 (IL-6), interleukin-10 (IL-10), and tumor necrosis factor-* (TNF-*). The cytokines will be assessed using dried blood spots. Moreover, socio-emotional functioning will be assessed with self-report questionnaires (e.g., depressive symptoms, anxiety, and social withdrawal). | — |
Secondary
| Measure | Time frame |
|---|---|
| Furthermore, we examine autonomic nervous system responses (galvanic skin conductance and ECG responses) and emotional responses to the standardized social stressor as additional outcomes. | — |
Countries
Netherlands
Outcome results
None listed