Psoriasis
Conditions
Interventions
None listed
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: * Age * 18 years. * Willing to sign the informed consent. * Diagnosis of psoriasis according to a dermatologist. * At least 1 psoriasis plaque with a sufficient total surface of at least 2.5cm x 3.5cm in order to execute TAP and TAPE procedure within one lesion. Alternatively, 2 psoriasis plaques on the same body region with a similar SUM score with a total combined surface of at least 2.5cm x 3.5cm may be used.
Exclusion criteria
Exclusion criteria: A potential subject who meets any of the following criteria will be excluded from participation in this study: * No diagnosis of psoriasis. * Diagnosis of other inflammatory skin disease. * Not willing to participate or sign informed consent. * Not willing to stop topical treatment on the day of sampling. * Age
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study endpoints are the Visual Analogue Scale (VAS) scores and the levels of cytokines measured by both TAP and TAPE procedure. The two VAS score (VAS-TAP and VAS-TAPE) will be used to study the possible discomfort and perception of patients by the removal of the TAP and the TAPE. | — |
Secondary
| Measure | Time frame |
|---|---|
| Not applicable. | — |
Countries
Netherlands
Outcome results
None listed