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Modulation of deep cortical regions by means of low intensity transcranial focused ultrasound (tFUS) neuromodulation

Modulation of deep cortical regions by means of low intensity transcranial focused ultrasound (tFUS) neuromodulation - Deep Ultrasound Neuromodulation (DUNe)

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON49840
Enrollment
40
Registered
2021-02-16
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The experiment is conducted on healthy participants. Using the proposed technique we aim at understanding the neural substrate of empathy emotions empathy

Interventions

None listed

Sponsors

Netherlands Institute for Neuroscience
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: healthy participants, age 18-35

Exclusion criteria

Exclusion criteria: A potential subject who does not meet any of the following criteria will be excluded from participation in this study: - Proficiency with the English language - Potential participants will be asked to fill a standard questionnaire for neuromodulation studies (TMS/tDCS) to exclude any participant with contraindications to brain stimulation/neuromodulation. * EXAMPLE OF SAFETY SCREENING * Have you ever: Had an adverse reaction to neuromodulation or ultrasound? Had a seizure? Had an EEG? Had a stroke? Had a head injury (include neurosurgery)? * Do you have any metal in your head (outside of the mouth,) such as shrapnel, surgical clips, or fragments from welding or metalwork? * Do you have any implanted devices such as cardiac pacemakers, medical pumps, or intracardiac lines, cochlear implants, implanted brain stimulators, implanted defibrillator? * Do you suffer from frequent or severe headaches? * Have you ever had any other brain-related condition? * Have you ever had any illness that caused brain injury? * Are you taking any medications? (e.g. Tricyclic anti-depressants, neuroleptic agents, and other drugs that lower the seizure threshold) * If you are a woman of childbearing age, are you sexually active, and if so, are you using a reliable method of birth control? * Does anyone in your family have epilepsy? * Do you need further explanation of the technique and its associated risks?

Design outcomes

Primary

MeasureTime frame
Primary outcome of the study will be participant performance in our task. (Behavioural Outcome)

Secondary

MeasureTime frame
-

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)