Bloedsomloop Circulation organ perfusion
Conditions
Interventions
None listed
Sponsors
HagaZiekenhuis
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: o Should be under PiCCO monitorization with routine clinic indication o Should be older than 18 years o Be suitable for monitoring in the intensive care unit o Eligible for sublingual microcirculatory evaluation (not to have maxillofacial injury, bleeding in the mouth)
Exclusion criteria
Exclusion criteria: o
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 2.1 Primary Objectives: o To investigate the correlation of microcirculatory parameter MFI measured with Cytocam-IDF with Cardiac Index measured using the trans-pulmonary hemodilution technique PiCCO. o To assess the association between the microcirculatory parameters and macro-hemodynamic parameters during admission and interventions such as fluid resuscitation and vasopressor/inotrope/vasodilator administration. | — |
Secondary
| Measure | Time frame |
|---|---|
| o To investigate the value and feasibility of routine monitoring of sublingual microcirculation as an early warning of clinical deterioration/improvement before the diagnosis can be made with laboratory, vital and hemodynamic parameters in critically ill patients. o To determine the usability of Cytocam-IDF in ICU practice, contribution for clinician's self-confidence, ease, time and cost. o To investigate the correlation between micro- and macro-circulatory alterations with global metabolic parameters, health status, laboratory/hemodynamic/vital parameters o To investigate the predictive value of microcirculation monitorization on the occurrence of complications like acute organ failure (renal failure, hepatic failure, encephalopathy, etc.) frequently seen in patients with fluid overload which may be visualized by measuring TVD and PVD alterations and compare to possible PICCO parameters for fluid overload. o To investigate the predictive value of microcirculatory alterations on patient survival. o To create a cut-off range for total vessel density, perfused vessel density and proportion of perfused vessels | — |
Countries
Netherlands
Outcome results
None listed