Skip to content

Beyond the window of risk? Psychiatric and functional outcome in adult bipolar offspring, a longitudinal study

Beyond the window of risk? Psychiatric and functional outcome in adult bipolar offspring, a longitudinal study - Dutch Bipolar Offspring Study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON49802
Enrollment
190
Registered
2020-02-13
Start date
2020-07-13
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bipolar disorder

Interventions

None listed

Sponsors

Erasmus MC, Universitair Medisch Centrum Rotterdam
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: In order to be eligible to participate in this study, bipolar offspring must meet all of the following criteria: Provided past consent to be re-contacted for future studies or contacted the research team by themselves. Give written informed consent for the current study. Healthy controls should be between 30 and 45 years old, and give written informed consent for the current study.

Exclusion criteria

Exclusion criteria: Subjects with a cognitive impairment sufficient to interfere with their ability to provide informed consent or complete study questionnaires. Healthy controls will be excluded when they have self-reported severe psychiatric disorders at present or in the past, or if they have a parent with bipolar disorder, schizophrenia, or major depressive disorder at present or in the past.

Design outcomes

Primary

MeasureTime frame
- Lifetime diagnosis of bipolar spectrum disorder based upon the Structured Clinical Interview for DSM-IV axis I disorders (SCID-I; First, Spitzer, Gibbon, & Williams, 1997).

Secondary

MeasureTime frame
- Functional outcome based upon the WHO-DAS 2.0, the Global Assessment of Functioning, and quality of life using the EQ-5D - Diagnoses of psychiatric disorders based upon the SCID-I - Daily mood fluctuations as measured by experience sampling (mobile assessment) - Daily functioning as measured using passive behavioural techniques including physical activity, social activity and daily rhythm

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)