Stress ten gevolge van houtrook acute stress asthma COPD
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Participant is 30 years or older Participant lives in the participating study area Participants for the asthma/COPD panel need to comply with the following criteria: o Self-reported doctors diagnosis of asthma/COPD. o Report of wheezing, shortness of breath And/or use of asthma/COPD medication in the past 12 months. Participants for the healthy adult panel need to comply with the following criteria: o No self-report of a doctor diagnosis of asthma/COPD ever o No report of wheezing, shortness of breath, chronic cough, phlegm in the past 12 months o No use of asthma/COPD medication in the past 12 months
Exclusion criteria
Exclusion criteria: Active smokers Subjects with a wood stove or fireplace People with absolute contra-indications for spirometry: o Heart attack in the last three months o Chest or abdominal surgery in the past 3 months o A brain, ear or eye surgery in the past 1 month
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study endpoints are lung function (FEV1 and PEF), daily respiratory symptoms, use of bronchodilator medication, and cortisol. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary parameters include inflammatory markers Interleukin (IL) 1b, IL-6, IL-8, IL-10, and tumour necrosis factor (TNF)*. | — |
Countries
Netherlands