Real-life and challenging gait skills to evaluate performance after cruciate-retaining total knee arthroplasy

Real-life and challenging gait skills to evaluate performance after cruciate-retaining total knee arthroplasy - Challenge CR

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON49702

Enrollment

Registered

2020-06-08

Start date

2020-08-27

Completion date

Unknown

Last updated

2024-07-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

degenerative joint disease Knee osteoarthritis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Patients undergoing total knee arthroplasty: 40-80 years old Non-inflammatory knee osteoarthritis as indicated by radiology Set to receive a primary total knee arthroplasty In stable health Healthy controls: 40-80 years old In stable health

Exclusion criteria

Exclusion criteria: Patients undergoing total knee arthroplasty: BMI > 35 Surgery to the study knee Active infection, systemic infection Trauma to study knee Previous knee, hip, or ankle replacement surgery or planned to have one in the next 24 months Any musculoskeletal or neurological disease other than osteoarhritis that impairs gait or balance Severe damage to any knee ligament other than anterior cruciate ligament Healthy controls: Moderate to severe pain in one or both knees, hip or ankle (>4 on items 3-6 form Brief Pain Inventory) Previous replacement surgery to knee, hip or ankle or planned for future replacement surgery

Design outcomes

Primary

Measure	Time frame
Difference between TKA-CR subjects 1 year post-operatively and healthy controls on average gait speed from gait bouts identified during 5-7 days continuous monitoring in real life (free-living).	—

Secondary

Measure	Time frame
Continous monitoring: - Quantity of gait bouts/hour - Peak turning velocity - Mean stride length - Mean stride time - Coefficient of variation of stride time - Asymmetry of step time - Coronal trunk range of motion - Foot strike angle Challenging gait tasks: Peturbations: - Foot placement post-perturbation - CoM trajectory during the perturbation and subsequent steps - Margin of stability - CoP trajectory - Spatiotemporal gait parameters (step width, step length) Up/downhill walking: - Sagittal knee moments - Knee adduction moments - Knee joint angles - Ankle joint moments and angles - Hip joint moments and angles - Toe-out angle - Toe-off angle - Spatiotemporal gait parameters	—

Measure

Time frame

Continous monitoring: - Quantity of gait bouts/hour - Peak turning velocity - Mean stride length - Mean stride time - Coefficient of variation of stride time - Asymmetry of step time - Coronal trunk range of motion - Foot strike angle Challenging gait tasks: Peturbations: - Foot placement post-perturbation - CoM trajectory during the perturbation and subsequent steps - Margin of stability - CoP trajectory - Spatiotemporal gait parameters (step width, step length) Up/downhill walking: - Sagittal knee moments - Knee adduction moments - Knee joint angles - Ankle joint moments and angles - Hip joint moments and angles - Toe-out angle - Toe-off angle - Spatiotemporal gait parameters

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Countries

Netherlands

Outcome results