Psychological Distress anxiety stress
Conditions
Interventions
Participants in the treatment group will follow an MBSR training which consists
of 8 weekly sessions lasting 2,5 hours
a silent day of approximately 6 hours
and daily home practice assignments of about 45 minutes. The control group will
follow the training at the end of the study, therefore acting as a wait-list
control group during the measurements.
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: Age above 18 years. Able to give informed consent. Score in Perceived Stress Scale score >= 16
Exclusion criteria
Exclusion criteria: Current specialised psychological or psychiatric treatment or medication. Insufficient comprehension of the Dutch language. Physical, cognitive, or intellectual impairments interfering with participation, such as deafness, blindness, or sensori-motor handicaps. Formerly/currently involved in MBCT or MBSR training. Current drug or alcohol addiction. Contraindications for MRI scanning (e.g., pacemaker, implanted metal parts, deep brain stimulation, claustrophobia, epilepsy, brain surgery, pregnancy).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure is perceived stress, which is measured by the Perceived Stress Scale (PSS) post-treatment. | — |
Secondary
| Measure | Time frame |
|---|---|
| We will also assess secondary outcome measures, including both self-reported questionnaires measuring depressive symptoms (Q-IDS-SR), anxiety (State and Trait Anxiety Inventory), alcohol use (AUDIT), childhood trauma (MACE-X), personality traits (NEO-FFI), repetitive negative thinking (PTQ), cognitive reactivity (LEIDS-R), allowing of emotions (Acceptance and Action Questionnaire), mindfulness skills (short version of the Five-Facet Mindfulness Questionnaire), self-compassion (short version of the Self-Compassion Scale), stress Resilience (CD-RISC), and positive mental health (Mental Health Continuum). Moreover, we will perform neurocognitive tasks that are selected specifically to assess exogenously as well as endogenously driven stress-regulation with and without task demands, including a fear conditioning and extinction paradigm, an emotional conflict resolution task, a resting state task under stress, and a real-time fMRI neurofeedback task. During these tasks we will record task performance, neuroimaging data (i.e. fMRI data), as well as physiological data (heart rate, respiration, skin conductance, pupil size, and salivary cortisol). In addition, we will administer ecological momentary assessments, coupled with physiological measures (heart rate, skin conductance, skin temperature, and movement), to assess stress reactivity in daily life. | — |
Countries
Netherlands
Outcome results
None listed