Quantifying various effects of closed-loop Spinal Cord Stimulation (SCS) on pathophysiological mechanisms in Complex Regional Pain Syndrome (CRPS); an explorative study

Quantifying various effects of closed-loop Spinal Cord Stimulation (SCS) on pathophysiological mechanisms in Complex Regional Pain Syndrome (CRPS); an explorative study - Closed-loop SCS for CRPS

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON49652

Enrollment

Registered

2020-08-18

Start date

2020-12-09

Completion date

Unknown

Last updated

2025-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

complex regional pain syndrome reflex sympathetic dystrophy

Interventions

Patients will receive standard care and will have all the standard follow-up visits and two additional visits. At every visit standard data is collected. However, at baseline and each follow-up visi

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: a subject must meet the standard Dutch Neuromodulation Society consensus criteria for spinal cord stimulation and the following study criteria:, - Over 18 year old - Diagnosed with retractable unilateral, upper- or lower limp CRPS, - Capable and willing to participate in the additional measurements.

Exclusion criteria

Exclusion criteria: - Pain of other aetiology in addition to CRPS, - Previously failed neuromodulation treatment (SCS or DRG).

Design outcomes

Primary

Measure	Time frame
The primary study parameter is the change in pain intensity at the end of the study compared with baseline.	—

Secondary

Measure	Time frame
Changes between the end of the study and baseline on all other parameters will be assessed and reported as secondary endpoints for this study.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)