inflammatie-gerelateerde ziekten infectieziekten Inflammation-related disease
Conditions
Interventions
None listed
Sponsors
Wageningen Universiteit
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • At least 18 years of age • Speaks Dutch • Works or lives at a dairy farm For the pilot study: at least 60 years of age
Exclusion criteria
Exclusion criteria: • A self-reported milk allergy or sensitivity to dairy ingredients • Mental status that is incompatible with the proper conduct of the study • Personnel of FrieslandCampina or Wageningen University & Research, department of Cell Biology and Immunology or Human Nutrition and Health
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main endpoint of the cohort study is the prevalence and incidence over time (if budget allows) of inflammation-related disease. The main study parameter of the feasibility study is the difference in age-related inflammatory markers IL-6, CRP, and sVCAM in serum between the two milk groups (mainly raw versus mainly UHT-processed cow*s milk). | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome of the cohort study is the prevalence and incidence over time (if budget allows) of auto-immune and infectious disease. The secondary outcomes of the pilot study are differences and variances in serum levels of the additional inflammatory markers TNF-a, sICAM-1, IL1RA. | — |
Countries
Netherlands
Outcome results
None listed