headache to nerve compression Neuralgia
Conditions
Interventions
Diagnostic nerve block at the site of local pain to confirm entrapment
neuropathy. If successful the subject is randomised between surgical
decompression or the standard medical treatment by the neu
Sponsors
Erasmus MC, Universitair Medisch Centrum Rotterdam
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - A local headache suspected to be neuralgia caused by compression neuropathy of one of the following peripheral nerves: * Supraorbital nerve * Supratrochlear nerve * Auriculotemporal nerve * Zygomaticotemporal nerve * Greater occipital nerve * Lesser occipital nerve * Third occipital nerve - The local headache not better accounted for by another headache diagnosis (although coexistence is possible)
Exclusion criteria
Exclusion criteria: - Known allergic reaction to bupivacaine - Cranial defects - Contraindications for general anesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score: average daily headache intensity o Measurement of headache intensity on a 10 point VAS. o Measure daily in a diary o Clinically relevant decrease defined as 50% or more | — |
Secondary
| Measure | Time frame |
|---|---|
| - Frequency of headache, defined as the number of days with headache per 28 days - Frequency of serious headache, defined as the number of days with headache per 28 days with a VAS of 5 or higher - Change in frequency of days with acute headache medication use per 28 days - Change in frequency of days with prophylactic medication use per 28 days - Change in frequency of days with analgesic medication use per 28 days - Loss of work. - CEQ - HIT-6 - SF-36 | — |
Countries
Netherlands
Outcome results
None listed