Differences in unaffected skin of patients with hidradenitis suppurativa compared with healthy controls.

Differences in unaffected skin of patients with hidradenitis suppurativa compared with healthy controls. - Is HS healthy skin healthy?

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON49510

Enrollment

Registered

2020-03-24

Start date

2020-04-01

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne inversa Verneuil's disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: In order to be eligible to participate in this study, HS patients must meet all of the following criteria: - Adults (* 18 years old) suffering from HS - Competent and willing to provide informed consent. In order to be eligible to participate in this study, healthy controls must meet all of the following criteria: - Adults (* 18 years old) not suffering from HS - Competent and willing to provide informed consent.

Exclusion criteria

Exclusion criteria: Exclusion criteria for HS patients: - Use of systemic or local antibiotics in the axillae or groin in the past 2 weeks - Use of any other medication potentially affecting the immune system or microbiome Exclusion criteria for healthy controls: -

Design outcomes

Primary

Measure	Time frame
Primary outcome: The difference in gene expression profile of unaffected skin from the axillae or groins of HS patients and healthy controls.	—

Secondary

Measure	Time frame
Secondary outcomes: 1. Microbial differences in uninvolved skin of HS axillae or groins and that of healthy controls. 2. Histological and immunohistochemical differences in uninvolved skin of HS axillae or groins and that of healthy controls	—

Countries

Netherlands

Outcome results