Abdominal aortic aneurysm
Conditions
Interventions
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: - Adult person (18 years or older) - Person has an abdominal aortic aneurysm or has previously been treated for an abdominal aortic aneurysm - Adequate comprehension of the Dutch language to provide written informed consent
Exclusion criteria
Exclusion criteria: - A patient who is decisionally impaired. The only exception to this are patients who are decisionally impaired due to effects of an acute abdominal aortic aneurysm. This particular group is eligible for participation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary study parameters/outcomes •AAA growth (mm/y). This will be measured using repeated imaging with either ultrasound, CT or MRI. •AAA rupture. This is defined as acute haemorrhage from the aneurysm outside the true aortic wall with the presence of intra-peritoneal and/or retroperitoneal blood at imaging, or observed during repair. •Death •Serum levels of cytokines (including, but not limited to IL- 6) •Serum levels of proteases (including, but not limited to MMP-9) •Protease and cytokine levels in aortic tissue | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study parameters/outcomes •During the course of the study, additional study parameters will be collected, as part of regular clinical care. For a full overview of all study parameters collected, please see the clinical data items titled PRISMA. PRISMA will contain all parameters collected during this project. Due to the longitudinal nature of this project, PRISMA may be subject to change. •Incidence of complications after AAA repair •Type of complications after AAA repair | — |
Countries
The Netherlands
Outcome results
None listed