aphasia and language disorders through brain damage CVA stroke
Conditions
Interventions
None listed
Sponsors
Radboud Universiteit Nijmegen
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • Between 18 - 78 years of age • Ischemic or haemorrhagic cerebral infarction • Postonset of approx. 2 months (subacute stage) for session 1, and 7 months (chronic stage) for session 2 • Native speaker of Dutch • Pre-morbidly right handed • Willingness and ability to give written informed consent and willingness and ability to understand the nature and content, to participate and to comply with the study requirements.
Exclusion criteria
Exclusion criteria: • History of previous stroke • Pre-existent cognitive problems • Severe aphasia (unable to understand instructions or provide consent). This will be predetermined by the referring neurologist or speech language pathologist, according to their usual practice • Use of psychotropic medication or recreational drugs • Pregnancy • Serious head trauma • Neurological or psychiatric disorders (other than stroke or epilepsy as a consequence of the stroke) • Large or ferromagnetic metal parts in the head (except for a dental wire) • Implanted cardiac pacemaker or neurostimulator • Claustrophobia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main study parameter is the task-related brain activity measured with electroencephalography and how it differs over time, together with patients* functional communication and memory performance for the included behavioural tasks. | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the effort that patients often experience in language use after stroke lesions, measured by tracking the heart rate and skin conduction due to sweat responses (GSR). | — |
Countries
Netherlands
Outcome results
None listed