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The effect of oxygen supplementation on oxidative stress in the Emergency Department.

The effect of oxygen supplementation on oxidative stress in the Emergency Department. - The short-term effects of osygen therapy on oxidative stress.

Status
Unknown
Phases
Unknown
Study type
Observational
Source
NL-OMON
Registry ID
NL-OMON49342
Enrollment
100
Registered
2020-04-21
Start date
Unknown
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

patienten met aandoeningen waarvoor zuurstof therapie noodzakelijk is voor of bij binnenkomst op de SEH Oxidative stress toxic effects of oxygen

Interventions

None listed

Sponsors

Universitair Medisch Centrum Groningen
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Non-trauma patients presenting to the ED who already receive oxygen therapy started by EMS or in whom oxygen therapy is started in the ED an in whom an infection is suspected - Adult (i.e. age > 18 years) - Able to provide (deferred) informed consent themselves or informed consent can be obtained via next of kin or legal gardian

Exclusion criteria

Exclusion criteria: - SpO2

Design outcomes

Primary

MeasureTime frame
The variation in FiO2, PaO2, SpO2 and levels of oxidative stress among patients with an infection admitted to the ED who receive oxygen therapy.—

Secondary

MeasureTime frame
- The correlation between baseline PaO2 and levels of oxidative stress in blood and urine in non-trauma ED patients receiving oxygen therapy; - To investigate if dynamic changes in PaO2 over time are related to changes in biomarkers of oxidative stress.—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)