blood flow measurements non-invasive cardiac output monitoring
Conditions
Interventions
None listed
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Adult patient (age > 18 years) - Elective coronary arterial bypass graft surgery and/or valve surgery - Informed consent
Exclusion criteria
Exclusion criteria: - Significant aortic valve stenosis > 30% without indication for valve repair, or abnormal anatomy of aortic, femoral, carotid or brachial artery 16 - Cerebrovascular accident - Atrial fibrillation or arrhythmias - COPD stage 3-4 - Severe heart valve regurgitation or stenosis - Inability to measure carotid artery blood flow or too low bifurcation - Contra-indications for femoral arterial catheter placement (e.g., vascular graft)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The accuracy of CO measured by ultrasound of the carotid blood flow will be compared to (1) thermodilution cardiac output measurement, (2) pulse-contour cardiac output measurement and (3) pulse-contour based non-invasive cardiac output measurement. These measurements are performed shortly after defined events in ICU patients when changes in the SVR are expected.The accuracy will be assessed by Bland-Altman analysis. We will describe if the limit of agreements are between ±30%. | — |
Secondary
| Measure | Time frame |
|---|---|
| - The variability or trending capability of CO measured by ultrasound of the carotid blood flow will be compared to (1) thermodilution cardiac output measurement, (2) pulse-contour cardiac output measurement and (3) pulse-contour based non-invasive cardiac output measurement calculated by concordance analysis and polar analysis, in short change in CO by ultrasound compared to change in CO by the reference CO. 13 - The bias of carotid blood flow measurement with ultrasound compared to (1) thermodilution cardiac output measurement, (2) pulse-contour cardiac output measurement and (3) pulse-contour based non-invasive cardiac output measurement calculated by Bland-Altman analysis and mean error. 13 - The response to therapy (directional changes) of carotid blood flow measurement with ultrasound compared to (1) thermodilution cardiac output measurement, (2) pulse-contour cardiac output measurement and (3) pulse-contour based non-invasive cardiac output measurement calculated by polar analysis. 13 | — |
Countries
Netherlands
Outcome results
None listed