Progressive Supranuclear Palsy
Conditions
Interventions
 
Participants are wearing the Verily studywatch for 12 months 
Sponsors
Radboud Universitair Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: * Subject has possible or probable PSP, according to the established international criteria defined by the Movement Disorders Society (MDS-PSP criteria, Höglinger et al, 2017); diagnosis is confirmed based on by consensus review of a videotaped neurological examination by two neurologists with deep expertise in movement disorders. In case the experts still have doubts, the treating physician will be asked to confirm the diagnosis and to send an MRI. If that additional information does not take away doubts about the diagnosis, the participant will be excluded. * Subject is an adult, at least 50 years of age. * Subject can read and understand Dutch. * Subject has completed the CMO-approved Informed Consent. * Subject is willing, competent, and able to comply with all aspects of the protocol. * Subject is able to walk at least 5 steps with or without minimal assistance (ie, stabilization of 1 arm or use of a cane or walker).
Exclusion criteria
Exclusion criteria: * Subject has an additional condition or situation that, in the opinion of the Investigator, makes the subject inappropriate for participation in the study. * For Study Watch: subject is allergic to nickel.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary objective is to develop algorithms for the detection of disease progression in PSP patients in key clinical parameters: bradykinesia, gait, rising from a chair and falls, based on (1) sensor data obtained by means of passive monitoring during daily living; and (2) sensor data collected during the Virtual Motor Exam. | — |
Secondary
| Measure | Time frame |
|---|---|
| The second objective of this study is to create a longitudinal dataset describing the clinical and functional characteristics of a representative PSP cohort to allow researchers to investigate important unanswered questions in PSP. | — |
Countries
Netherlands
Contacts
Public ContactMJ Meinders
Radboud Universitair Medisch Centrum
Outcome results
None listed