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Effects of a combination of heat and hypobaric hypoxia on cognitive performance.

Effects of a combination of heat and hypobaric hypoxia on cognitive performance. - Hypoxia and heat load

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON49264
Enrollment
21
Registered
2020-03-11
Start date
2020-09-16
Completion date
Unknown
Last updated
2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cognitieve prestatie(verlies) cognitive performance deterioration effort

Interventions

The exposure to a single condition takes a total of 105 minutes, where the first 60 minutes simulate the *flight preparation/ground procedures part* (with potential heat load stimuli) and the next 4

Sponsors

TNO
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Healthy (as defined by exclusion criteria) • Age between 18 - 35 years • BMI between 18 and 25 kg/m2 • No alcohol the evening before the start of a test day • No drugs used in the last 3 months • Medically screened: questionnaire & electrocardiogram (ECG) • Physically capable of sitting in a warm environments for about 2 hours

Exclusion criteria

Exclusion criteria: • Cardio-vascular disorders (including cardiac implantable devices like pacemakers and ICDs) • Psychiatric or neurological disorders • Claustrophobic • Hypersensitive to air sickness • Color blindness • Smoking • Pregnant • Being at altitude (above 2 kilometers) in the last 3 months for longer than a week

Design outcomes

Primary

MeasureTime frame
Cognitive performance measured by: - Multi-Attribute Task battery-II (MATB-II) The outcome variables are as follow: • System monitoring: Number of successfully tuned off/on lights Percentage omissions Mean response time Number of false reactions • Tracking task Root mean square (RMS) target tracking error • Resource management task Mean absolute deviation from target fuel level • Communication Number of successful radio and frequency tunings Number of false reactions Mean response time - SYNWIN multiple-task battery Individual task performance metrics include: • Memory task percent correct and RT for correct responses; • Math task percent correct and RT for correct responses; • Visual Monitoring task point score and lapse rate (number of times subject allowed gauge to reach zero divided by number of sampling periods); • Auditory Monitoring percent correct. - The Vigilance & Tracking (VigTrack) • Root mean square tracking error • Percentage omissions • Number of false reactions • Reaction times - Psychomotor Vigilance Task (PVT) • Reaction time • Lapses • Misses

Secondary

MeasureTime frame
- Perceived workload measured with the NASA-Task load Index (TLX) - Rating of subjective mental effort (RSME) - Skin temperature in degrees Celsius - Core temperature in degrees Celsius - Percentage SpO2 - Heart Rate in beats per minute - Sweat rate - Score on visual task Other outcome measures - Subjective thermal perception score - Experienced hypoxia symptoms - Operative temperature (WBGT) Besides this, participants* age and gender will be recorded in order to describe our sample and for possible later use as covariates.

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)