Does stimulation of salivary glands by oral intake increase uptake and toxicity of PSMA-ligands?

Does stimulation of salivary glands by oral intake increase uptake and toxicity of PSMA-ligands? - Stimulation of salivary glands with intake

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON49260

Enrollment

Registered

2020-06-11

Start date

2020-08-20

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dry mouth xerostomia

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Received PSMA PET/CT on clinical indication (

Exclusion criteria

Exclusion criteria: - Poor quality of the baseline PSMA PET/CT scan - Planned start or changes in treatment between the baseline scan and study scan. - Age

Design outcomes

Primary

Measure	Time frame
The accumulation of systemically administered PSMA-ligands in salivary glands on PET/CT.	—

Secondary

Measure	Time frame
To screen for potential influence of oral intake on the biodistribution of PSMA-ligands on PET/CT in other organs and tumour.	—

Countries

Netherlands

Outcome results