geen aandoening not applicable
Conditions
Interventions
Given the between-subjects design, subjects will either receive placebo or 200
mg modafinil. The medication will be administered orally. The participants will
be asked to perform various tests relat
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: • In the opinion of the investigator, the participant is capable of understanding and complying with protocol requirements. • The participant is male or female. • The participant has a body mass index of 18.5-30 kg/m2, inclusive, as stated in the medical screening form. • The participant is aged 18 to 40 years, inclusive, at the time of informed consent. • The volunteer is healthy, i.e., the absence of all exclusion criteria and had normal or corrected to normal static binocular acuity with or without correction. • The participant signs and dates a written informed consent form before the start of the experiment.
Exclusion criteria
Exclusion criteria: • The subject has an uncontrolled, clinically significant neurologic, cardiovascular, pulmonary, hepatic, renal, metabolic, gastrointestinal, or endocrine disease or other abnormality which may impact the ability of the subject to participate or potentially confound the study results. • The volunteer has uncontrolled existing major psychiatric symptoms. • The participant has known hypersensitivity to any component of the formulation or Modafinil or related compounds. • The subject has a history of drug abuse (defined as any illicit drug use) or a history of alcohol abuse within 1 year prior to the first visit or is unwilling to agree to abstain from alcohol from 24 hours prior to each test day and/or drugs throughout the study. • The participant has any sensory or motor deficits which could reasonably be expected to affect test performance. • Other exclusion criteria are smoking, excessive drinking (>20 glasses of alcohol-containing beverages a week), use of medication. • For females, exclusion criteria are taking the birth control pill and being pregnant.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are behavioral data from economic decision-making paradigms. In particular, elicited parameters describing preferences over risk, time, and losses. | — |
Secondary
| Measure | Time frame |
|---|---|
| Social preferences, trust, and reciprocity are secondary parameters, as well as cognitive performance on our control tasks. | — |
Countries
Netherlands
Outcome results
None listed