Skip to content

Assessment of the glycemic responses to nutritional products

Assessment of the glycemic responses to nutritional products - GLOW

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
NL-OMON
Registry ID
NL-OMON49247
Enrollment
10
Registered
2019-11-04
Start date
2019-11-18
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

niet van toepassing

Interventions

- Several nutritional products containing 25 or 50 grams of carbohydrates (testproduct) - Standard glucose solution (reference product) (250 ml, contains 25 or 50 grams of glucose)

Sponsors

Nutricia Research
Lead Sponsor

Eligibility

Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Age * 18 and * 60 years 2. Body Mass Index (BMI) * 18.5 and * 24.9 kg/m2 3. Written informed consent 4. Willingness and ability to comply with the protocol 5. Judged by the investigator to be in good health

Exclusion criteria

Exclusion criteria: 1. Known Diabetes Mellitus type I or type II, rebound hypoglycemia and/or any other medical condition that interferes with glucose metabolism 2. Any use of anticoagulants, steroids, protease inhibitors or antipsychotics and/or any medication known to affect glucose tolerance and/or to influence digestion and absorption of nutrients within 1 week of screening, in opinion of the investigator 3. Any known disease which influence digestion and absorption of nutrients within 1 week of screening 4. Any known food allergy or intolerance 5. Adherence to a strict vegan diet and/or a weight loss program 6. Any known bleeding disorder

Design outcomes

Primary

MeasureTime frame
GI = Capillary blood glucose iAUC0-120 [mmol/l] of test product/ mean capillary blood glucose iAUC0-120 [mmol/l] of reference product

Secondary

MeasureTime frame
- GL=GI*available carbohydrate/given amount - Capillary blood glucose mmol/l and iAUC0-120 [mmol/l*min] of the reference product and test product(s) - Capillary blood glucose iCmax [mmol/l] and Tmax [min] of the reference product and test product(s) - Appetite profile and liking of the test product using visual analogue scales

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)