Quality of life and burden of disease in patients with hypoparathyroidism after thyroid surgery in the Southwestern region of the Netherlands.

Quality of life and burden of disease in patients with hypoparathyroidism after thyroid surgery in the Southwestern region of the Netherlands. - Quality of life in patients with persistent postsurgical hypoparathyroidism

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON49191

Enrollment

225

Registered

2019-01-25

Start date

2019-03-19

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypoparathyroidism inadequate secretion of parathyroid hormone

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Patients who are aged 18 years or older at the time of inclusion - Patients who gave informed consent - Both cases and controls underwent (completion) thyroidectomy - Cases have persisting hypoparathyroidism according to the previously mentioned definition and controls do not

Exclusion criteria

Exclusion criteria: - Patients who are not able to provide written informed consent - No adequate understanding of the Dutch language - Parathyroid disease or parathyroid surgery

Design outcomes

Primary

Measure	Time frame
Main study endpoints are quality of life in patients with hypoparathyroidism as measured by the physical component score of the SF-36. Other endpoints are cognitive and functional outcomes and burden of disease (eg. extra visits, employment status, comorbidities).	—

Secondary

Measure	Time frame
The secondary objectives of this study are: - To determine the Thyroid-Related quality of life in patients with hypoparathyrodism - To determine the cognitive and functional outcomes in patients with hypoparathyrodism - To determine the burden of disease in patients with hypoparathyroidism (eg. Medication use, the absence of work/return to work, extra hospital visits, comorbidities, hypoparathyroidism related laboratory parameters)	—

Measure

Time frame

The secondary objectives of this study are: - To determine the Thyroid-Related quality of life in patients with hypoparathyrodism - To determine the cognitive and functional outcomes in patients with hypoparathyrodism - To determine the burden of disease in patients with hypoparathyroidism (eg. Medication use, the absence of work/return to work, extra hospital visits, comorbidities, hypoparathyroidism related laboratory parameters)

—

Countries

Netherlands

Outcome results