incomplete spinal cord injury, stroke incomplete spinal cord injury, stroke
Conditions
Interventions
None listed
Sponsors
University of Twente
Eligibility
Age
16 Years to 99 Years
Inclusion criteria
Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: • age between 16 and 85, • legal capacity to give the consent at his/her own will; for the stroke individuals: • hemiparesis of the lower limb at chronic stage (> 3 months); • impaired plantar flexion during walking • MRC Grade 3 and above for the calf • FAC score of 3 and above • Ability to walk at least 6 minutes at their self-selected walking speed. for the SCI individuals: • chronic stage: time since SCI > 12 months, • clear walking impairment but able to walk independently (without support), i.e. Walking Index for Spinal Cord Injury (WISCI) > 1 and spinal cord independence measure (SCIM) > 30, • Motor incomplete spinal cord injury (ASIA impairment scale: C or D), • Injury situated superior to the T9 vertebra. • Ability to walk at least 6 minutes at their walking speed.
Exclusion criteria
Exclusion criteria: Individuals fulfilling one of the following criteria will be excluded: Motor complete spinal cord injury (ASIA impairment scale: A or B), • neuromuscular disease, • pregnancy, • addictive or previous addictive behaviour defined as the abuse of cannabis, opioids or other drugs, • carrier of infectious diseases, • degenerative mental impairment, e.g. dementia, • inability to cooperate, e.g. due to cognitive deficits (in understanding instructions) or a level of motor impairment that does not permit execution of the intended tasks, • subjects suffering from known cardiac conditions (e.g., pacemakers, arrhythmias, and cardiac conduction disturbances) or peripheral neuropathy. • skin sensitivity or allergies as these are typical contraindications for the application of surface EMG electrodes via adhesive elements and conductive gels. • Participating in an ongoing study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome of this study are models capable of estimating the following neuro-mechanical parameters: joint kinematics, human-machine interaction forces, amplitude of mechanically-induced reflexes, and motor neuron parameters (e.g. discharge rate, inter-spike intervals and coherence between spike trains). | — |
Secondary
| Measure | Time frame |
|---|---|
| All the subjects will be asked to fill out a questionnaire that assesses physical and physiological factors that may be of relevance for the analysis. These characteristics are the following: • Sex • Age (years) • Weight (kg) • Height (m) • Leg length (m) • Use of sedatives and analgesics • Other neurological disorders than stroke/SCI • Chronic pain • History of depression • History of diagnosed cognitive deficit | — |
Countries
Netherlands
Contacts
Public ContactM. Sartori
University of Twente
Outcome results
None listed