cognitieve prestatie(verlies) door slaapdeprivatie cognitive resilience
Conditions
Interventions
None listed
Sponsors
TNO
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. The potential participant has given informed and written consent and is able to comply with all study assessments scheduled in the protocol. 2. All subjects need to be between 18 and 55 years of age. 3. All subjects has computer skills. 4. All subjects need to be in good health, and may not have any chronic diseases. 5. BMI between 18 and 30 kg/m2. 6. No alcohol the day before the start of a test day. 7. No drugs used in the last 3 months. 8. Subjects must be able to communicate, participate, and comply with the requirements of the entire study. 9. One week prior to starting every trial day, all subjects need to be (and remain) in the same time zone as the CET time zone in which the research center lies. (GMT+1, daylight savings GMT+2). This to exclude jet lags that might confound the test results. 10. No signs of flue or viral infection in the last 10 days before the start.
Exclusion criteria
Exclusion criteria: 1. Smoking 2. Pregnant 3. A history of psychiatric illness; this including sleeping disorders. 4. Autoimmune disease and/or hyperactive thyroid 5. People with known heart, kidney or liver disease or neurological complaints.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Main study parameters/endpoints are inflammatory responses. These will be assessed using capillary blood samples obtained from finger pricks. The main primary endpoints of cognitive resilience will be defined as the difference between cognitive performance measures before and after the night. Cognitive resilience to SD refers to the extent to which a sleep deprived individual maintains cognitive performance while sleep deprived. | — |
Secondary
| Measure | Time frame |
|---|---|
| - Cognitive performance determined based on the PVT - HR and EDA during Psychological Synchrony - Stanford Sleepiness Scale (SSS) - Rating Scale of Mental Effort (RSME) | — |
Countries
Netherlands
Outcome results
None listed