obstipation
Conditions
Interventions
personalized advice based on their habitual food pattern (as assessed using a
food frequency questionnaire) and preferences. Based on a special algorithm,
the PDA provides high fiber alternatives fo
Sponsors
Wageningen Universiteit
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: - Age *18 years and
Exclusion criteria
Exclusion criteria: - Subjects with a disease that may interfere with the personal dietary advice or outcomes, such as a known autonomic disorder, inflammatory bowel disease, coeliac disease, cancer, dialysis patients, chronic kidney failure, depression or hypothyroidism. - Currently following strict diet and unwilling or unable to change; for example a gluten free diet or a *crash diet* using meal substitutes. - Use of medication that can interfere with the study outcomes, including diuretics, antidepressants, codeine, antibiotics or fiber supplements. Preferably laxative use is excluded, but if recruitment is hurdled by this, we at least exclude specific laxatives like resolor, relistor and constella. These are laxatives who have a significant impact on bowel movements, and are only available on prescription. Osmotic (over the counter available) laxatives will be included if recruitment is difficult. Subjects will then be asked to keep their laxative use stable or reduce, but not to increase usage from their habitual pattern (unless necessary, but then report it to the researchers). Moreover, additional questions regarding laxative usage will be included to estimate the effect of laxatives on stool pattern. - Female subjects: currently pregnant or breastfeeding, or intending to become pregnant during the study, as this can affect stool patterns and wellbeing. - Are simultaneously participating in another study. - Unwilling or unable to fulfil the study criteria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| primary outcomes are stool pattern, gastro-intestinal complaints and constipation quality of life and severity. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary parameters include dietary fiber intake, physical activity, body weight, psychological questionnaires, and fecal microbiota composition and metabolite levels. Furthermore, the PDA will be evaluated. | — |
Countries
Netherlands
Outcome results
None listed