Non-invasive MR imaging of vulnerable carotid artery plaque characteristics

Non-invasive MR imaging of vulnerable carotid artery plaque characteristics - MR imaging of carotid artery plaque deformation

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON49132

Enrollment

Registered

2019-07-26

Start date

2018-05-08

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

arteriosclerosis atherosclerotic plaque inflammation in the vessel wall

Interventions

Atherosclerosis

Carotid

Deformation

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: * Patients only: Known with an atherosclerotic lesion in (one of) the carotid arteries of at least 2 mm thick causing 30-99% stenosis [ECST guideline * Healthy volunteer only: Should consider himself/herself as 'healthy' and not known with any major cardiovascular diseases

Exclusion criteria

Exclusion criteria: * 100% stenosis (total occlusion) * MRI contraindications

Design outcomes

Primary

Measure	Time frame
To assess reproducibility of the new MRI techniques acquiring carotid artery plaque deformation during the cardiac cycle.	—

Secondary

Measure	Time frame
To correlate plaque deformation with plaque components that are most likely apparent in (vulnerable) atherosclerotic plaques (e.g. lipid-rich necrotic core, fibrous cap, calcifications and fibrous tissue)	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)