cartilage damage of the ankle
Conditions
Interventions
Both groups of patients are surgically treated with arthroscopic bone marrow
stimulation (BMS). The control group will receive BMS alone but with a
sham-treatment consisting of a Jamashidi (bone mar
Sponsors
Academisch Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: • Patients with a symptomatic OCL of the talus who are scheduled for arthroscopic debridement and microfracture • OCL depth and/or diameter
Exclusion criteria
Exclusion criteria: • Concomitant OCL of the tibia • Ankle osteoarthritis grade 2 or 3 • Ankle fracture
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure is the difference in pain during weight-bearing between pre-operative and 24 months after surgery on a numeric rating scale (NRS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary parameters are: - Questionnaires: EQ5D, AOFAS, FAOS, NRS (in rest, during running, during stair-climbing, during performing sports), FAAM, SF-12, Ankle Activity Scale (AAS), return to sports, return to work - Radiological outcomes: CT-scan (depth, wide, length, joint space measurement) and MRI scan (T2 relaxation times) - Cost-effectiviness - Cell-subset analysis - Complications, Re-operations, Demographic data | — |
Countries
Netherlands
Outcome results
None listed