spierfunctie exercise performance
Conditions
Interventions
The intervention will be carried out with 5 different prebiotics supplements
suitable for human consumption. Thefollowing prebiotics are selected
(commercially available):
1. Dietary intake or galac
Sponsors
Universiteit Maastricht
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: 1. Aged from 18- 40 years 2. 18.5
Exclusion criteria
Exclusion criteria: 1. Smoking 2. Performing regular resistance training (3+ times per week, carrying out progressive training) 3. Subject following an overly imbalanced or restrictive diet as per nutritional advice 4. Concurrent systemic disease and/or laboratory abnormalities considered by investigators to be detrimental for the participants safety or potentially interfering with the study procedures and/or study outcome 5. Hypertension (according to WHO criteria) and/or cardiovascular disease 6. Abdominal surgery interfering with gastrointestinal function, upon judgement of the medical doctor, who will decide in-or exclusion based on the surgery applied 7. Participants who received antibiotics in the previous 90 days to the start of study 8. Use of other medication will be reviewed by a medical doctor, who will decide on in- or exclusion based on the drug(s) used 9. Use of laxatives within 14 days prior to the study 10. Using medications for gastric or intestinal complaints 11. Drug use, interfering with any of the outcome parameters of this study; to be decided by the person who is medically responsible for this study 12. Self-admitted lactose intolerance 13. Having donated blood in the 3 months prior to the study 14. Administration of probiotic or prebiotic supplements, investigational drugs or participation in any scientific intervention study, which may interfere with this study (to be decided by the principle investigator), in the 14 days prior to the study 15. History of side effects towards intake of prebiotic supplements 16. Use of proton pump inhibitors
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The most important parameter is the outcome of the exercise test until exhaustion. | — |
Secondary
| Measure | Time frame |
|---|---|
| - the fecal microbiota - biomarkers of metabolic health; fasting glucose, insulin and SCFA - SCFA concentration in the droppings - permeability of the intestines after a single exercise test - permeability of the intestines after intervention | — |
Countries
Netherlands
Outcome results
None listed