A screening protocol to collect a blood sample for the pharmacogenetic profiling of metabolic enzymes and drug transporters in male and female volunteers.

A screening protocol to collect a blood sample for the pharmacogenetic profiling of metabolic enzymes and drug transporters in male and female volunteers. - CS0327 - Genotyping

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON49124

Enrollment

500

Registered

2019-10-28

Start date

2019-10-28

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pharmacogenetics genetic pharmacological research pharmacogenetics

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Provision of written informed consent. 2. Male and female subjects aged >=18 years.

Exclusion criteria

Exclusion criteria: 1. Previous participation in the current screening protocol. 2. The subject is, in the opinion of the Investigator, unlikely to comply with the protocol or considered unsuitable for this study. For instance, when drawing 20 mL of blood is exclusionary for a planned participation in a QPS clinical trial.

Design outcomes

Primary

Measure	Time frame
Distribution of genotype of p-Gp, BCRP, OATP1B1, OATP1B, OAT1, OAT3, OCT1, OCT2, MATE1, 5-HTTLPR, CYP1A2, CYP2D6, CYP2C9, CYP2C19, CYP3A4.	—

Secondary

Measure	Time frame
N.ap.	—

Countries

Netherlands

Outcome results