Identifying risk factors in the immune profile of patients with a SARS-CoV-2 infection

Identifying risk factors in the immune profile of patients with a SARS-CoV-2 infection - Immune monitoring in COVID-19 patients

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON49107

Enrollment

100

Registered

2020-05-04

Start date

2020-05-11

Completion date

Unknown

Last updated

2026-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronavirus infection COVID-19

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: * Age 18 years and older; * Proven SARS-CoV-2 infection; * Patient will be admitted to either the general COVID ward or the Internsive Care unit; * Written informed consent.

Exclusion criteria

Exclusion criteria: * Unable to provide written informed consent.

Design outcomes

Primary

Measure	Time frame
To investigate the baseline systemic immune profile in COVID-19 patients using mRNA expression profiling, and to connect that to clinical outcome in order to identify prognostic and predictive markers that can help in decision making for individual patients.	—

Secondary

Measure	Time frame
* To investigate the individual systemic immune profile changes in COVID-19 patients using mRNA expression profiling, and to connect that to clinical outcome. * To scrutinize the pathogenesis of COVID-19 by connecting the circulating immune profile to that infiltrated in the lung samples of deceased patients.	—

Countries

Netherlands

Outcome results