Oxidative stRess drIver Of male iNfertility: ORION study

Oxidative stRess drIver Of male iNfertility: ORION study - ORION study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON49093

Enrollment

Registered

2020-11-26

Start date

2021-01-05

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

male infertility

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: In order to be eligible to participate in this study, a subject must meet all of the following criteria: males of couples visiting the Center of Reproductive medicine at the UMCG between 18-55 years old.

Exclusion criteria

Exclusion criteria: * Males who receive(d) chemo- and/or radiotherapy, use(d) testosterone suppletion and/or anabolic steroids * Males who have an abnormal SA due to genetic causes. * Semen analysis with round cells >2x106 /ml (as marker for infection)

Design outcomes

Primary

Measure	Time frame
The main study parameter will be free thiols in patients with oligo-asthenospermia and patients with normospermia.	—

Secondary

Measure	Time frame
Concomitant measurable antioxidants. General health parameters: - BMI - Comorbidities - Medication - Level of degree Lifestyle parameters: - Diet - Physical activity - Smoking - Illicit drug use - Toxic exposure at work	—

Countries

Netherlands

Outcome results