Unique epigenetic, transcriptional, metabolomic and proteomic characterization of the heart in cardiomyopathy patients

Unique epigenetic, transcriptional, metabolomic and proteomic characterization of the heart in cardiomyopathy patients - DECIPHER-PLN part 2

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON49085

Enrollment

Registered

2020-10-06

Start date

2020-11-26

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cardiomyopathy Heart disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • A minimum age of 18. • Of adequate communication. • Informed consent is obtained.

Exclusion criteria

Exclusion criteria: • Known allergy for local anaesthetics.

Design outcomes

Primary

Measure	Time frame
Define the biological pathways affected in several types of cardiomyopathies using a multi-omics approach. We will furthermore define how cardiac PLN expression correlates to skeletal muscle PLN expression to see whether PLN expression in skeletal muscle can be used as a proxy for PLN expression in the heart.	—

Countries

Netherlands

Outcome results