Habituation to pain in healthy subjects: An fMRI-EEG study using a multilevel approach

Habituation to pain in healthy subjects: An fMRI-EEG study using a multilevel approach - Habituation to pain: An fMRI-EEG study

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON49084

Enrollment

Registered

2020-12-09

Start date

2021-05-07

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

nvt nvt

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Age 18-65

Exclusion criteria

Exclusion criteria: - MRI contraindications (pacemaker, claustrophobia, vein clip, pregnancy, etc.) - Chronic (> 3 months) or recurrent pain in the last three months or other chronic diseases that may intervene with chronic pain, such as diabetes - Current use of psychotropic medication - Reported psychiatric or neurological disorders - Reported regular use of so-called recreational drugs (e.g., cannabis)

Design outcomes

Primary

Measure	Time frame
The main study parameter is Blood Oxygen Level Dependent (BOLD) activity, measured using fMRI. BOLD activity of areas over time will be modeled.	—

Secondary

Measure	Time frame
- Brain activity measured with EEG - Pain ratings during the habituation protocol. After each painful stimulus, the subject will rate the pain on a VAS scale. - Pain ratings during the intensity protocol. After each painful stimulus, the subject will rate the pain on a VAS scale.	—

Countries

Netherlands

Outcome results