apathy listlessness psychosis
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients: - At least 18 y.o.a. - Diagnosis schizophrenia - Maximum score AES (27) - Stable medication use (at least 4 weeks prior to inclusion) - Written informed consent - Participants should have a normal level of exercise tolerance and no physical handicaps that limit their radius of action - Participants should have weekends, wherein they are free from work (i.e. do not have to work weekend shifts), Healthy subjects: - At least 18 y.o.a. - Maximum score AES (27) - Written informed consent - Participants should have a normal level of exercise tolerance and no physical handicaps that limit their radius of action - Participants should have weekends, wherein they are free from work (i.e. do not have to work weekend shifts)
Exclusion criteria
Exclusion criteria: Patients: - An apathy score above 27 on the apathy subscale of the AES-C - Current disorder of substance abuse (excluding nicotine addiction) - Insufficient Dutch language abilities, Healthy subjects: - History of or current psychiatric or neurological illness - An apathy score above 27 on the apathy subscale of the AES-S - Insufficient Dutch language abilities
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameters are activity level (Acti-meter) and the degree of apathy (AES). | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary study parameters are negative symptoms, general psychopathology, depression and the ability to experience pleasure (PANSS, SANS, CDSS and TEPS). | — |
Countries
Netherlands