Immune mechanisms during preterm sepsis

Immune mechanisms during preterm sepsis - IMPRESS

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON49081

Enrollment

300

Registered

2020-07-26

Start date

2021-04-15

Completion date

Unknown

Last updated

2025-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

blood-poisoning, sepsis

Interventions

None listed

Eligibility

Age

No minimum to 11 Years

Inclusion criteria

Inclusion criteria: Preterm and term newborns with a gestational age of 24 weeks to 42 weeks of gestation who are admitted at the Erasmus Medical Centre-Sophia Children*s Hospital

Exclusion criteria

Exclusion criteria: Parents that do not have sufficient understanding of the Dutch language and are therefore not able to comprehend the patient information sheet

Design outcomes

Primary

Measure	Time frame
To characterize the in vitro immune response of preterm and term newborns against sepsis-related bacteria during the first ten weeks after birth	—

Secondary

Measure	Time frame
To compare the in vitro immune response of umbilical cord blood with the immune response of preterm and term newborns in the first months of life	—

Countries

Netherlands

Contacts

Public ContactH.R. Taal

Erasmus MC, Universitair Medisch Centrum Rotterdam

onderzoek.neonatologie@erasmusmc.nl010-7040704

Outcome results