Feasibility and preliminary effectiveness of a preoperative training and nutrition intervention in people with sarcopenic obesity who receive total hip or knee arthroplasty within the 'Actief Herstel' care pathway

Feasibility and preliminary effectiveness of a preoperative training and nutrition intervention in people with sarcopenic obesity who receive total hip or knee arthroplasty within the 'Actief Herstel' care pathway - Preoperative training and nutrition in the 'Active Recovery' care pathway

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON49062

Enrollment

Registered

2020-04-02

Start date

2021-05-03

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sarcopene obesitas Sarcopenic obesity / Muscle weakness and overweight

Interventions

The intervention group will follow a supervised (by a physiotherapist) exercise intervention of 6 weeks (twice a week) with progressive strength training and aerobic training. This will be combined

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: • Scheduled for THA or TKA with a waiting period of minimal 6 weeks (which is the usual waiting period) • Osteoarthritis as reason for surgery • Having obesity (BMI >=30 kg/m2) • Having muscle weakness (Men: Hand Grip Strength (HGS) 15sec for five rises) • Adequate cognitive functioning (the patient is capable to understand instructions and to per-form the screening) • Age 18 years or older

Exclusion criteria

Exclusion criteria: Patient • unable to understand Dutch; • diagnosed with dementia; • who are unable to exercise due to comorbidities/ contra-indications. Absolute contra-indications for exercise are listed in the Dutch guideline for osteoarthritis and in the ACSM's Guidelines for Exercise Testing and Prescription; • with severe renal insufficiency or an eGFR

Design outcomes

Primary

Measure	Time frame
Feasibility is assessed by adherence to treatment, inclusion rates, drop out rates and adverse events and complications. The amount of attended training sessions attended and the achieved intensity are noted. The physical activity (accelerometer) and food intake (food diary) are also measured. The appreciation and motivation of the patient will be assessed with questionnaires.	—

Secondary

Measure	Time frame
Effectiveness is assessed by measuring physical functioning (timed up and go test, hand grip strength, walking speed/ six-minute walk test, chair rise time test, questionnaires), body composition (BIA/ DEXA) and inflammation (IL-6), before and after 6 weeks of intervention. In addition, postoperative inpatient complications, CRP, recovery of physical functioning and length of hospital stay will be assessed. Furthermore, nutritional intake (3-day food diary) and physical activity (by accelerometer) will be measured.	—

Measure

Time frame

Effectiveness is assessed by measuring physical functioning (timed up and go test, hand grip strength, walking speed/ six-minute walk test, chair rise time test, questionnaires), body composition (BIA/ DEXA) and inflammation (IL-6), before and after 6 weeks of intervention. In addition, postoperative inpatient complications, CRP, recovery of physical functioning and length of hospital stay will be assessed. Furthermore, nutritional intake (3-day food diary) and physical activity (by accelerometer) will be measured.

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Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)