The longitudinal relation between hyposmia and other (non-)motor symptoms in Parkinson's disease - an observational study

The longitudinal relation between hyposmia and other (non-)motor symptoms in Parkinson's disease - an observational study - Follow-up of olfactory function in Parkinson's disease

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON49039

Enrollment

100

Registered

2020-03-31

Start date

2020-08-17

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson Parkinson's disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: *Included in the baseline cohort with a diagnosis of Parkinson's disease according to the UK PD Society Brain Bank criteria *Be able to understand the aim of the current follow-up study, understand the study procedure and be able to give written informed consent

Exclusion criteria

Exclusion criteria: *Diagnosis changed from PD to another form of parkinsonism *Unwillingness to be informed of unexpected medical findings *Lack of mastery of Dutch language

Design outcomes

Secondary

Measure	Time frame
-disease duration (years) -Unified Parkinson's disease Rating Scale - motor score (UPDRS III) -Mini-Mental State Exam (MMSE) -Montreal cognitive assessment (MoCA) -scales for outcomes of Parkinson's disease (SCOPA)-Sleep -SCOPA-autonomic dysfunction -SCOPA-psychiatric complications -Beck Depression Inventory (BDI) -Beck Anxiety Inventory (BAI) -Cognitive tests: Digit Span, Stroop Color-Word test, Letter fluency, Category fluency, Rey's auditory Verbal Learning Test, clock drawing -Modified Hoehn & Yahr stage -Body Mass index (length/weight) -Blood pressure (lying down, 1 min standing, 3 min standing) -Medication Use (levodopa equivalent dose)	—

Measure

Time frame

-disease duration (years) -Unified Parkinson's disease Rating Scale - motor score (UPDRS III) -Mini-Mental State Exam (MMSE) -Montreal cognitive assessment (MoCA) -scales for outcomes of Parkinson's disease (SCOPA)-Sleep -SCOPA-autonomic dysfunction -SCOPA-psychiatric complications -Beck Depression Inventory (BDI) -Beck Anxiety Inventory (BAI) -Cognitive tests: Digit Span, Stroop Color-Word test, Letter fluency, Category fluency, Rey's auditory Verbal Learning Test, clock drawing -Modified Hoehn & Yahr stage -Body Mass index (length/weight) -Blood pressure (lying down, 1 min standing, 3 min standing) -Medication Use (levodopa equivalent dose)

—

Primary

Measure	Time frame
Olfactory function, measured with University of Pennsylvania Smell Identification Test (UPSIT)	—

Countries

Netherlands

Outcome results