The microlesion effect on cognition after Deep Brain Stimulation in Parkinson's disease

The microlesion effect on cognition after Deep Brain Stimulation in Parkinson's disease - Microlesion effect on cognition after DBS

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON49024

Enrollment

Registered

2020-05-20

Start date

2020-11-16

Completion date

Unknown

Last updated

2024-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's disease

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Adults (over the age of 18 years) that are selected for DBS in the STN by the multidisciplinary working group Oral- and written informed consent

Exclusion criteria

Exclusion criteria: Unstable internal or other pathologies Not able to apprehend the consequences of surgical intervention Depression or other psychiatric instabilities Dementia (Mattis Dementia Rating Scale (DRS)

Design outcomes

Primary

Measure	Time frame
The primary endpoints of the study are the SDMT, Stroop and WAIS part IV Digit Span scores to assess the MLE on cognitive functioning.	—

Secondary

Measure	Time frame
The MoCA score on the day before the surgery and at 12 months, to assess the predictive value of perioperative cognitive functioning (MoCA scores are correlated to SDMT, Stroop and WAIS part IV Digit Span scores to assess this topic).	—

Countries

Netherlands

Outcome results