Dialysis Hemodialysis
Conditions
Interventions
None listed
Sponsors
Haaglanden Medisch Centrum
Eligibility
Age
18 Years to 99 Years
Inclusion criteria
Inclusion criteria: All subjects must be able to participate and be willing to give written informed consent and to comply with the study restrictions. In addition, eligible subjects must meet the following inclusion criteria:;- Patients male/female > 18 years old that are on hemodialysis using an arteriovenous fistula (AVF) or arteriovenous graft ( AVG) and are capable of giving written informed consent.
Exclusion criteria
Exclusion criteria: 1. Concomitant disease or condition that could interfere with the conduct of the study or the study objectives, or that would, in the opinion of the investigator, pose an unacceptable risk to the study participant. 2. Condition of the skin that prohibits accurate LSCI measurements, such as large tattoos, skin ulcers, scar tissue, etc. 3. For group 2: prior vascular access surgery on contra or ipsilateral arm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| * correlation of finger and toe pressures with LSCI and shuntflow measurements | — |
Secondary
| Measure | Time frame |
|---|---|
| * Variability of microcirculation measured with LSCI in hemodialysis patients. * Association between shuntflow and basal blood flow measured with microcirculation measurements using LSCI * * LSCI (blood flow upon occlusion/reperfusion) and shunt flow * Effect of a hemodialysis session on finger and toe pressures and LSCI basal blood flow * Correlation between blood flow upon occlusion/reperfusion ( endothelial function) using LSCI in hemodialysis patients and retrospective good/poor AVF maturation. | — |
Countries
Netherlands
Outcome results
None listed