anesthesie voor utrologische laparoscopische ingrepen anesthesia narcosis
Conditions
Interventions
anesthesia
neuromuscular block
relaxation
surgical rating
Sponsors
Leids Universitair Medisch Centrum
Eligibility
Age
18 Years to 64 Years
Inclusion criteria
Inclusion criteria: (i) Patients diagnosed who are will undergo an elective laparoscopic renal surgical procedure, i.e. (donor) nephrectomy (ii) ASA class I-III (iii) > 18 years of age; (iv) Ability to give oral and written informed consent.
Exclusion criteria
Exclusion criteria: (i) Known or suspected neuromuscular disorders impairing neuromuscular function; (ii) Allergies to muscle relaxants, anesthetics or narcotics; (iii) A (family) history of malignant hyperthermia; (iv) Women who are or may be pregnant or are currently breast feeding; (v) Renal insufficiency, as defined by serum creatinine x 2 of normal, or urine output 35 kg/m2
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main end-point of the study is the effect of the deep block on surgical conditions during sevoflurane anesthesia. To that end-the surgical team will be asked to rate the quality of the surgical field at 15-min intervals using the 5-point Leiden-Surgical Rating Scale (L-SRS), a scale that was previously developed at LUMC and recently validated | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary end-points of the study are hemodynamics (blood pressure and heart rate) and Nociception Level (NoL [3]) during anesthesia, and pain and sedation scores following surgery. | — |
Countries
The Netherlands
Outcome results
None listed