The influence of stress on Parkinsons tremor a behavioural pilot study

The influence of stress on Parkinson*s tremor * a behavioural pilot study - Effect of stress on Parkinson's tremor

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48944

Enrollment

Registered

2018-10-15

Start date

2019-01-30

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's disease tremor

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: - Idiopathic Parkinson*s disease according to UK brain bank criteria. - Presence of a clear resting tremor of at least one arm (UPDRS tremor-score >

Exclusion criteria

Exclusion criteria: - Neuropsychiatric co-morbidity - Cognitive impairment (MMSE

Design outcomes

Primary

Measure	Time frame
During each of the three behavioral tasks we will record the following primary outcome measures: - Tremor power (quantified using accelerometry and EMG) - Pupil diameter (a marker of noradrenergic activity; quantified using eye tracking)	—

Secondary

Measure	Time frame
Additionally, we will obtain measure of: - Task performance (using choice and reaction times) - Heart rate (quantified using ECG) - Disease severity (UPDRS part III and TRS)	—

Countries

Netherlands

Outcome results