Optical spectral transmission imaging for treatment monitoring and correlation with arterial stiffness in patients with rheumatoid artritis starting with TNF inhibiting therapy

Optical spectral transmission imaging for treatment monitoring and correlation with arterial stiffness in patients with rheumatoid artritis starting with TNF inhibiting therapy - Handscan PWV

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48787

Enrollment

Registered

2018-01-16

Start date

2018-02-01

Completion date

Unknown

Last updated

2024-06-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

inflammatory arthritis rheumatoid arthritis

Interventions

None listed

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Rheumatoid arthritis group - 18 years or older - Active rheumatoid arthritis in hands or wrists, defined as * 2 swollen hand joints (IP, PIPs and/or MCPs) or * 1 swollen wrist joints;Hypertension group - 18 years or older - Patients with hypertension, defined as systolic blood pressure >140 mmHg and/or diastolic blood pressure >90 mmHg or currently on antihypertensive treatment - No rheumatoid arthritis;Healthy controls group - 18 years or older - No hypertension, defined as systolic blood pressure *140 mmHg, diastolic bloodpressure * 90 mmHg and no antihypertensive treatment - No rheumatoid arthritis

Exclusion criteria

Exclusion criteria: - Surgery in wrist or hand in the preceding 3 months - Other active concomitant musculoskeletal disease

Design outcomes

Primary

Measure	Time frame
The main study parameters are the results from the handscan measurement, arterial stiffness as measured with pulse wave velocity and augmentation index, DAS28 and the ultrasound assessment of the hand joints at all time points (baseline, 1 month and 4 months).	—

Countries

Netherlands

Outcome results