Neuro-Cardiac-Guided Transcranial Magnetic Stimulation: a method to probe the depression network. Replication and dose-response.

Neuro-Cardiac-Guided Transcranial Magnetic Stimulation: a method to probe the depression network. Replication and dose-response. - NCG-TMS: replication and dose-response

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

NL-OMON

Registry ID

NL-OMON48765

Enrollment

Registered

2018-01-04

Start date

2018-03-16

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depression MDD

Interventions

All participants receive the same intervention. Session 1: 1 minute of iTBS on 7 different cortical brain locations. Session 2: 1 minute of iTBS spread over 2 different cortical brain locations, wit

Eligibility

Age

18 Years to 99 Years

Inclusion criteria

Inclusion criteria: Healthy, between the ages of 18-60.

Exclusion criteria

Exclusion criteria: Similar to TMS exclusion criteria: no prior experience with epilepsy, no pregnancy or wish for pregnancy within the period of the research. No metal in the head or cochlear implants.

Design outcomes

Primary

Measure	Time frame
Heart rate converted to RR intervals. The troughs of these intervals are used as input in analysis.	—

Secondary

Measure	Time frame
Gender, head size, age and motor threshold.	—

Countries

Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)