Impaired sensory processing in Autism Spectrum Disorder: Towards better phenotyping and cellular models*

Impaired sensory processing in Autism Spectrum Disorder: Towards better phenotyping and cellular models* - BECAUSE: From Behavior to Cell in Autism Sensory Processing.

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

NL-OMON

Registry ID

NL-OMON48762

Enrollment

240

Registered

2019-12-19

Start date

2017-11-01

Completion date

Unknown

Last updated

2024-02-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Autism ASD

Interventions

Autism

E/I inbalance

Induced Pluripotent Stem cells (iPSCs)

Sensory Processing

Eligibility

Age

18 Years to 64 Years

Inclusion criteria

Inclusion criteria: Diagnosis of Autism Spectrum Disorder, parent or sibling of person with Autism Spectrum Disorder or Control Scoring extreme high or low (7th percentile) on the Sensory Processing questionnaire.

Exclusion criteria

Exclusion criteria: Control Participants are excluded if -they have an IQ score below 80), based on educational attainment (Mavo/VMBO or higher); -if they are younger than 20 or older than 55 years; -if they have a diagnosis of autism, or score above the cutoff on the Autism Quotient Questionnaire, Participants with autisem are excluded if they are -not clinically diagnosed with autisme

Design outcomes

Primary

Measure	Time frame
1. Self-reported behavioural questionnaire on sensory processing 2. Self-reported behavioural questionnaire on daily life functioning, such as clinical severity, social problems, educational attainment, and wellbeing 3. Neuropsychological tasks on sensory processing 4. Neurophysiological (i.e., EEG) parameters 5. Polygenic Risk Scores 6. Cellular assays	—

Secondary

Measure	Time frame
nvt	—

Countries

The Netherlands

Outcome results

None listed

Source: NL-OMON (via WHO ICTRP)