Tumoren in darm, lever of pancreas waarvoor resectie gepland is Colorectal cancer hepatic cancer pancreatic cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: - More that 18 years of age; - Scheduled for elective colorectal, hepatic, or pancreatic resection at Maastricht UMC+; - A low physical fitness according to the preoperative screening with the advice to participate in the hospital's prehabilitation program (usual care); - Willing to participate in the hospital's prehabilitation program (usual care); - Providing informed consent to participate; - After informed consent, classified as being at risk for a complicated postoperative period (VAT *11 mL/kg/min at the pre-prehabilitation CPET).
Exclusion criteria
Exclusion criteria: - Patients requiring acute (emergency) surgery; - Patients undergoing surgery in another hospital than Maastricht UMC+; - Patients with contraindications for physical exercise training; - Unable to cooperate with the testing procedures (e.g., insufficient understanding of the Dutch language).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The main study parameter is the feasibility (adherence/compliance, adverse events, and patient appreciation) of a four-week home-based prehabilitation program in individual high-risk patients scheduled for elective colorectal, hepatic, or pancreatic resection. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary parameters are to explore: 1) individual responses to the program (physical fitness), 2) changes in immune system activity, 3) changes in nutritional status, 4) changes in quality of life, 5) changes in health status, and 6) short-term postoperative outcomes (e.g., and time to recovery of physical functioning, 30-day morbidity). | — |
Countries
Netherlands